[PDF] A detailed 3D MRI brain atlas of the African lungfish Protopterus annectens | Semantic Scholar (2024)

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@article{Lozano2024AD3, title={A detailed 3D MRI brain atlas of the African lungfish Protopterus annectens}, author={Daniel Lozano and Jes{\'u}s L{\'o}pez and Adri{\'a}n Chinarro and Ruth Morona and Nerea Moreno}, journal={Scientific Reports}, year={2024}, volume={14}, url={https://api.semanticscholar.org/CorpusID:268957486}}
  • D. Lozano, Jesús López, N. Moreno
  • Published in Scientific Reports 5 April 2024
  • Biology, Environmental Science

The results confirm that lungfish show neuroanatomical patterns reminiscent of those of extant basal sarcopterygians, with an evagin*ted telencephalon, and distinctive characters like a small optic tectum, indicating that their brain may contain significant clues to the characters of the brain of ancestral tetrapods.

63 References

Comparative Analysis of Nkx2.1 and Islet-1 Expression in Urodele Amphibians and Lungfishes Highlights the Pattern of Forebrain Organization in Early Tetrapods
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Analysis ofression patterns of Nkx2.1 and Islet-1 (Isl1), which encode transcription factors that are key in the regionalization of the forebrain, were analyzed by combined immunohistochemical methods in young adult specimens of two lungfishes and a urodele amphibian to get insights into the possible organization of theForebrain in the common ancestor of all tetrapods.

Pax6 expression highlights regional organization in the adult brain of lungfishes, the closest living relatives of land vertebrates
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The detailed distribution of Pax6 cells in the adult central nervous system of lungfishes helps to understand the primitive condition that would have characterized the common ancestors to all sarcopterygians (lobe‐finned fishes and tetrapods), in which Pax6 would be needed to maintain specific entities of subpopulations of neurons.

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